Two Loci Controlling Genetic Cellular Resistance to Avian Leukosis-Sarcoma Viruses

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Genetic resistance to avian viruses.

Viral infections of poultry can be catastrophic in terms of both welfare and economics, and although vaccines have been very successful in combating these diseases, new forms of viruses have evolved which present increasing difficulties for vaccine control. Differences in genetic susceptibility are known to exist for many of the major viral pathogens of poultry. Consequently, an increase in the...

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Proposal for numbering mutants of avian leukosis and sarcoma viruses.

A system for the numbering of mutants of avian sarcoma and leukosis viruses is proposed.

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CAR1, a TNFR–Related Protein, Is a Cellular Receptor for Cytopathic Avian Leukosis–Sarcoma Viruses and Mediates Apoptosis

Viral envelope (Env)-receptor interactions have been implicated in the cell death associated with infection by subgroups B and D avian leukosis-sarcoma viruses (ALVs). A chicken protein, CAR1, was identified that permitted infection of mammalian cells by these viral subgroups. CAR1 bound to a viral Env fusion protein, comprising an ALV-B surface Env protein and the Fc region of an immunoglobuli...

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Immunofluorescent studies of group-specific antigen of the avian sarcoma-leukosis viruses.

2 O'Conor, G. T., A. S. Rabson, A. Malmgren, I. K. Berezesky, and F. J. Paul, J. Natl. Cancer Inst., 34, 679 (1965). 8 Rowe, W. P., and S. G. Baum, J. Exptl. Med., 122, 955 (1965); Schell, K., W. T. Lane, M. J. Casey, and R. J. Huebner, these PROCEEDINGS, 55, 81 (1966). 4 Huebner, R. J., R. M. Chanock, B. A. Rubin, and M. J. Casey, these PROCEEDINGS, 52, 1333 (1964). 6 Rowe, W. P., and S. G. Ba...

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Ultrastructure of the surfaces of cells infected with avian leukosis-sarcoma viruses.

When stained with ruthenium red (RR), chick embryo cells infected with various strains of Rous sarcoma virus (RSV) and with avian leukosis viruses RAV-1 and RAV-3 showed an increase in the layer of acid mucopolysaccharides (AMPS) at their surfaces as compared with uninfected cells. This increase was most prominent in cells infected with the Fujinami strain of RSV. The layer was resistant to dig...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 1967

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.1.5.898-904.1967